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Some tumors secrete cytokines that promote angiogenesis (neovascularization), thereby increasing their fuel supply and enhancing tumor growth

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Cultures were subsequently fed at day in vitro (DIV) 4 with 1 mL of Neurobasal-A medium supplemented with 1% rat serum, B-27, Anti-Anti, glutamine and AraC

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Other small compounds are also described as ferroptosis inducers, including two FDA-approved drugs, sulfasalazine, prescribed for lung carcinoma and fibrosarcoma (50, 51) and sorafenib (52)