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Medical and Lifestyle Strategies to Minimize Facial Aging Dermatologists recommend three proactive approaches: (1) maintain aggressive skincare with retinoids and vitamin C serums to support collagen production, (2) ensure adequate hydration and protein intake to preserve skin elasticity and muscle mass, and (3) consider non-invasive treatments like microneedling or radiofrequency to stimulate collagen remodeling as facial fat redistributes

Finan B, Ma T, Ottaway N et al (2013) Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans

People with a history of severe gastrointestinal issues, such as gastroparesis (delayed stomach emptying), should avoid this medication, as it can exacerbate these conditions

But besides fat, patients also lose muscle mass, which can be an unwelcome side effect

Mol Metab 70:101692 Muskiet MHA, Tonneijck L, Smits MM, Van Baar MJB, Kramer MHH, Hoorn EJ et al (2017) GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetes