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While more research is needed, these properties make BPC-157 an intriguing candidate for supporting brain health and potentially benefiting individuals dealing with cognitive decline, brain injuries, or age-related neurodegenerative disorders

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For example, increased Rac1 activity, either through KO/knockdown of Rac1 upstream GAP proteins such as alpha-chimaerin and BCR/ABR, or the expression of constitutively active Rac1 mutants, led to unstable theta-burst stimulation (TBS)-induced LTP that gradually decayed to the baseline response at the CA1 synapse (Oh et al., 2010

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10.1016/j.ebiom.2021.103475 112 JiangY.-Q.ChangG.-l.WangY.ZhangD.-Y.CaoL.LiuJ