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Response: We appreciate the commenters for feedback on the proposed comparison approach and our proposal to not use a predetermined performance threshold of final scores within our payment methodology

Horses that received 0.3 mg Se/kg dry matter (DM) had greater citrate synthase activity in the gluteus medius muscle at rest compared to horses supplemented with 0.1 mg Se/kg DM [Se supplemented as Se-yeast

In contrast, PT-141 targets the central nervous system by activating the melanocortin receptors in the hypothalamus, which play a key role in regulating sexual arousal

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