This finding holds significant importance, noting that phase 3 studies have typically excluded patients with a history of psychiatric disorders, resulting in a lack of reference data for understanding the long-term consequences of GLP-1 RAs use in patients with obesity
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Figure 3 ALC and LC Levels Differ Before and After Treatment Since the collection of blood samples after treatment was not considered at the beginning of the study, as well as the impact of the new coronary pneumonia epidemic and the time of hospitalization for 50%, the content of LC and ALC increased significantly after antidepressant treatment
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3.6.3 Mechanisms linking gut dysbiosis to PSCI 3.6.3.1 Neuroinflammation Gut dysbiosis and increased intestinal permeability following ischemic stroke (IS) have been linked to systemic endotoxemia and altered microbial metabolite signaling, potentially exacerbating neuroinflammation and injury (Zhang W