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[DOI] [PubMed] 31.Berezhnov AV, Fedotova EI, Nenov MN, Kasymov VA, Pimenov OY, Dynnik VV

Muscle cramps: L-carnitine 300 mg administered 3 to 4 times daily for 8 weeks in patients with cirrhosis

The mitochondrial membranes are impermeable to coenzyme A(CoA) esters and long-chain fatty acids, binding of L-carnitine to acetyl groups via carnitine acyltransferase is essential for the shuttle of the acetylated fatty acids into the mitochondria and their subsequent oxidation

Pain relief was linked to improvements in clinical symptom scores and morphometric parameters of sural nerve biopsy, ie the increased fiber numbers and clusters of regenerating fibers