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Being closely related to obesity, a new term has emerged in recent years: Diabesity, considered a modern epidemic, which indicates the coexistence of both diabetes and obesity [23]

Saxenda's mechanism of action includes glucose-dependent insulin secretion and suppression of glucagon release, leading to improved blood glucose regulation

An increase in SERT expression leads to lower enteric serotonin levels and contributes to constipation-predominant IBS (IBS-C), while a decrease in SERT expression increases serotonin levels in the gut and can be a factor in IBS-D

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