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Furthermore, AKG can decrease protein degradation in muscles, and plays a protective role in the gut

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Also, in the case of 3D cultures, Western blotting analysis demonstrated that angiotensin-converting enzyme and CD40 were upregulated, and that sirtuin 1 and sirtuin 6 were inhibited after TNF- treatment

Additionally, the presence of perinuclear antineutrophil cytoplasmic antibodies (ANCA) has emerged as a potential biomarker for disease activity

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