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Evidence suggests that Nurr1 and Pitx3 cooperate to regulate the expression of DA neurotrophic factors such as brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor, as well as genes critical for DA neurotransmission, thereby promoting VTA DA neuron survival and the acquisition of mature DA phenotypes (Martinat et al., 2006

The concomitant topical treatment of wounds with antibiotics or other local agents has never given rise to interactions or incompatibilities with Bionect

14 - 19 Also, there are very limited extension of the standard cytoprotectants effect from the stomach lesions to other organs lesions (liver, pancreas), 20 , 21 thus a quite limited cytoprotective and organoprotective therapeutic potential

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