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Pregnancy outcome after first trimester exposure to corticosteroids: A prospective controlled study

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If left unchecked, this can lead to the progressive loss of kidney function or to abnormalities in the kidneys structure, both of which often show no signs until theyve reached an advanced stage

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Direct scavenging of free radicals (especially ROS), inhibition of ROS manufacturing enzymes, and preservation of mitochondrial integrity and function affect redox signaling by activating nuclear factor erythroid-derived 2-like 2 (Nrf2) and peroxisome proliferator-activated receptor alpha (PPAR), and the synthesis of heat shock proteins (HSPs), thioredoxins, sirtuins, and other antioxidant molecules are pathways through which L-carnitine and its derivatives modulate oxidative stress conditions [14, 38]

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