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Therefore, the need for new therapies able to cure and prevent the progression of this condition is increasingly urgent

In the Study of Tirzepatide in Participants with Heart Failure with Preserved Ejection Fraction with Obesity (SUMMIT) trial, tirzepatide significantly reduced the risk of death from cardiovascular causes or worsening heart failure events in patients with heart failure with preserved ejection fraction (ejection fraction 50% and above) and obesity (BMI 30 kg/m 2 ), compared with placebo (HR 0.62

Pricing also differs: oral tirzepatide's ongoing monthly rate ranges from $129 to $229 depending on plan length, notably lower than injectable tirzepatide's $280 to $449 range

"Neuromodulation of Pelvic Visceral Pain: Review of the Literature and Case Series of Potential Novel Targets for Treatment"

Sep 2016;4(5):857-65