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Iron abundance, proneness to oxidative stress, the role of Ca 2+ signaling in cell death, and the capability of other erythroid lineage cells to undergo ferroptosis all together indicate that this iron-driven cell death pathway might exist in RBCs

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Dans des conditions normales, plus de 98 % du glutathion intracellulaire est sous forme rduite GSH, et le GSSG ne reprsente que 1 2 % du pool total