The SUSTAIN (Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes) trial series began enrolling patients in 2012, ultimately encompassing multiple phase 3 trials with thousands of participants worldwide
The rationale for 2 independently functioning systems to control satiety remains unexplained
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This result suggests that GLP-1RAs may help control overeating but could also reduce eating-related satisfaction
"Dehydroascorbate reduction"