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Based on the Rome IV criteria, which was updated in June 2016, the gold standard for the diagnosis of IBS is the exclusion of other diseases (Mearin et al., 2016)

Individuals with higher baseline C-peptide levels achieved greater improvements in time-in-range than those with lower endogenous insulin secretion

Those taking GLP-1 receptor agonists with insulin or sulphonylureas should carry fast-acting carbohydrates at all times