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Additionally, melanoma cells resistant to BRAF/MEK inhibitors showed a permanent expression of NRF2 and nuclear translocation through increased mitochondrial activity [156]
Regulation of cellular senescence via the FOXO4-p53 axis
In addition, complex non-medical regimensoften involving the concurrent use of multiple agents such as thyroid hormones, growth hormone, insulin analogues, stimulants, or other performance- and physique-enhancing substancesfurther hinder interpretation of reported outcomes
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