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As expected, silencing of endogenous KEAP1 increased luciferase activity driven by ARE elements under Cyss depletion conditions, whereas simultaneous expression of exogenous shRNA-resistant KEAP1 restored basal expression (Fig

Since stretch marks cause a disruption in the natural production of collagen, microneedling will help not only restart that production, but the overproduction of elastin and collagen will help in healing the damaged connective tissue in the dermis that creates the stretch mark