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It is the mechanism

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The ScanBrit randomised, controlled, single-blind study of a gluten-and casein-free dietary intervention for children with autism spectrum disorders

This latter observation suggests the possibility that oxidative stress is consequential in the reported compensatory rise in subcellular melatonin production, as commonly observed in plants and which has also been reported in algae (97, 107), which in turn upregulates the SIRT3/FOXO/SOD2 pathway, thereby helping to maintain oxidative homeostasis under elevated oxidative stress conditions

Clinical data suggests this mechanism helps prevent the metabolic adaptation that typically slows weight loss over time with other interventions