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The induction of defense response occurred in the early infection phase at 3 days post-inoculation and it was consistent with lower levels of disease severity in resistant cultivars (Veluchamy and Panthee, 2015)

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Clin Chem 49, 901-7 (2003)

Beyond DHFR inhibition, MTX and the polyglutamate forms impede de novo purine synthesis and thymidylate synthase, intensifying the cytotoxic effects that affect cell proliferation and growth (Mohamed et al., 2019)

Over the past year, pharmaceutical companies and healthcare providers accelerated efforts to position these medications