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This process involves the activation of a cascade of caspase enzymes, particularly caspase-3, which executing apoptosis through the cleavage of key intracellular substrates

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Comparison with published datasets showed that circulating eosinophils resembled Clec4a4 + arylhydrocarbon receptor (AHR)-dependent regulatory eosinophils from the small intestine (Wang et al, 2022), while inflammatory eosinophils II shared features with Clec4a4 - proinflammatory subsets (Fig