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What to supplement: Start with low doses of methylated B vitamins (e.g., 400-800mcg methylfolate, 500-1000mcg methyl-B12) Increase gradually while monitoring symptoms Include B6 and other B-complex vitamins Retest homocysteine after 2-3 months If low homocysteine is accompanied by low SAMe: If testing shows both low homocysteine and low SAMe, you may benefit from methylation support

After rapid weight loss, many patients experience a condition that causes excess sagging skin around parts of their body, affecting their proportions and silhouette

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This finding does not rule out that TGF-B at higher doses, or other cytokines presumably involved in penile growth such as IGF1 (see next page), may be able to decrease penile ARs