glycine in glp 1 GLP-1 supplements are everywhere—but do they actually work? As demand for weight-loss drugs grows, companies are cashing on products that claim to support GLP-1 goals, often with little oversight. Tap the How to Avoid the Side

Monitoring your progress Supplementation without monitoring is guesswork

Expert Opin Investig Drugs (2011) 20:171722

However, its a stimulant that can be habit-forming

Other research highlights: 30% of GLP-1 users tested positive for SIBO or IMO even after accounting for diabetes (5) GLP-1 medicines caused microbiome changes and altered metabolism in mice (6) GLP-1 medicines tested in humans only had noticeable microbiome changes by 48 weeks (7) Despite not necessarily having slower gut motility, one study found that 88.9% of obese patients had SIBO (8) A meta analysis of people with IBS symptoms, found that up to 78% of people had SIBO, many of whom were undiagnosed (9) Overall, Sun and colleagues (1) could not prove a mechanistic link between GLP-1 medications and SIBO, however they did find that SIBO was twice as likely in GLP-1 users

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