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Third, the causal relationship between ferroptosis and stone pathogenesis lacks rigorous validationexisting data only confirm oxalate induces ferroptosis, but it remains unclear whether ferroptosis directly promotes crystal adhesion, tubular injury, or inflammatory responses (key steps in stone formation) or is merely a secondary consequence of oxalate toxicity

Sacheck, J

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The body's cells become resistant to insulin, or the pancreas does not produce enough of it, or both - while glucagon continues to drive blood sugar higher

Ali N, Muoz K, Degen GH (2017b) Ochratoxin A and its metabolites in urines of German adultsan assessment of variables in biomarker analysis