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Because the weight loss process on GLP-1s is so fast, she said people need to be extra vigilant in their nutritional intake, specifically increasing their intake of protein, to avoid sarcopenic obesity

| How the calculator works | Why we dont recommend counting | How to reach your target without counting | Why we cap deficits at 15% | Recalculating as you lose weight | Targets by medication | Factors that affect your needs | FAQs | Take home message To lose weight sustainably on GLP-1 medications while maintaining muscle mass, you should eat a calorie deficit of between 10-15%

The drugs, which work by suppressing appetite, are not suitable for everyone and can have severe side effects

A detailed review could help identify these gaps and propose directions for future research [Risks and benefits of antioxidant supplement use during cancer treatment (12)]

Cardenolides have a five-membered ring at C17, while bufadienolides have a six-membered lactone ring at C17 with two double bonds (Mijatovic et al., 2007)