This relationship allows it to modulate copper-dependent enzymes and deliver copper to cells in a safe, effective manner
Chemokines (CCchemokine ligand 2 (CCL2) and CXCchemokine ligand 10 (CXCL10)) and pro-inflammatory mediators (TNF and IL-6) secreted either from the activated endothelium (10) or from surrounding immune cells further increase leukocyte adhesion and promote crawling over the luminal endothelial surface (9)
That said, side effects can occur: Common side effects (mild and transient) Injection site reactions: Redness, mild swelling, or tenderness at injection sites
Sharygin D, Koniaris L G, Wells C, et al
Following this study, the efficacy of ixekizumab on the scalp was also evaluated in a randomized phase III clinical trial comparing ixekizumab 80 mg at 2-week dosing intervals, 4-week dosing intervals, and 4- to 2-week interval dose adjustment groups