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The HFD was purchased from CLEA Japan Inc., Tokyo, Japan

I-VIT 12 Injection can only be administered at home if instructed by a healthcare professional

However, it is important to note that erythrocytes generate ROS primarily as a result of (i) hemoglobin oxidation, which can be considered as an iron-mediated Fenton reaction, (ii) the activity of NAPDH oxidase and (iii) xanthine oxidoreductase, while in nucleated cells ROS are mainly generated in the mitochondrial electron transport chain

Submaximal VO 2 was lower during exercise bouts at 45% and 65% VO 2 peak

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