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PTC tends to spread lymphatically, but the probability of lymph node metastasis in PTC associated with HT is low (Anand et al

Ren Z, Zou C, Ji H, Zhang YA (2010) Oestrogen regulates proliferation and differentiation of human islet-derived precursor cells through oestrogen receptor alpha

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Nevertheless, uncritical enthusiasm is unwarranted given the pervasive heterogeneity of existing trials, the profound dependence of therapeutic effects on formulation characteristics, and the inherent limitations of predominantly short-duration interventions in a disease defined by decades of progressive metabolic deterioration

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