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Drawbacks: Injections require a visit to a healthcare professional, can be uncomfortable, and are often more expensive than supplements

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The requirements for activation of distinct calcium sources for induction of plasticity further changed in older animals (P35 5)

Keck et al., 2017) and play a role during development or recovery after injury and deafferentation, cannot serve the homeostatic function for fast-scale Hebbian-type plasticity (for further discussion see Chistiakova et al., 2014, 2015

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