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Pre-existing risk factors common in the diabetes population further compound concern: Older age (reduced intrinsic factor production) Autoimmune conditions (pernicious anaemia, thyroid disease) Previous gastric surgery or gastrointestinal disorders Vegetarian or vegan dietary patterns There is no established link between semaglutide pharmacology and B12 metabolism in the MHRA-approved product information, but the clinical context in which Ozempic is prescribed creates a population where B12 awareness is prudent

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Therefore, if the body is deficient in vitamin B12, the level of MMA is likely to increase

Clinical Trial Dosing Data AOD-9604 has been evaluated across multiple administration routes and dosing regimens