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MGF (mechano-growth factor, the IGF-1Ec splice variant) is a natural alternative splice product of the IGF-1 gene, upregulated by mechanical loading and muscle damage, distinguished by a unique C-terminal E-peptide

Glucagon Like Peptide-1 is a single, non-glycosylated, polypeptide chain containing 30 amino acids and having a molecular mass of 3298.7 Dalton

The protein can also cause apoptosis (cellular suicide), and in senescent cells, FOXO4 communicates with p53 to prevent this

We found a significant fold increase in the levels of several tumor suppressor and DNA repair gene protein products (GP)s at the end of 4th week during 4-week intermittent fasting (CALU, INTS6, KIT, CROCC, PIGR), and 1 week after 4-week intermittent fasting (CALU, CALR, IGFBP4, SEMA4B) compared with the levels before 4-week intermittent fasting

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