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It was shown that paraoxonase-1 (PON1) and arylesterase activity were decreased (the arylesterase activity linked to PON1 is known to protect lipoproteins from oxidation) and there was also a decrease in the total antioxidant status

Hyperchromic macrocytic megaloblastic anemia (pernicious anemia, Biermer's anemia, Addison's anemia - these are maturation disorders of the red blood cells)

It should be high in leafy greens (Folate helps arsenic metabolism) and brightly colored fruits and vegetables, which contain many antioxidants (like vitamin C, Vitamin E, glutathione, carotenoids, and flavonoids) that support the tissues to some degree from the damaging effects of toxic metals and may help to chelate metal ions

PMID 26182315

The definition of Alzheimer's and other dementias used in the Framingham Study was very strict