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In the fast 8 mg arm, nausea, vomiting, and diarrhea rose to 30% to 35% and remained elevated

A 2019 systematic review published in the National Library of Medicine identified improvements in skin brightness across several small trials while emphasising the need for larger controlled studies before definitive claims can be made

The widespread presence of numerous pollution agents both outdoor (air, water, soil) and indoor (air, water supplies, chemicals used in house cleaning, etc.) without forgetting foods that are frequently highly processed and filled with chemicals used mostly to improve flavors, palatability and conservation

doi: 10.1136/bmj-2022-070750 2 HortonJSterrenburgMLaneSMaheshwariALiTCCheongY

Medical monitoring is necessary to avoid unsafe use and prompt intervention should side effects develop