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Reduced expression of 1AMPK is observed in the GCs of women with PCOS, and this is accompanied by higher steroidogenesis due to the increased activity of 3-hydroxysteroid dehydrogenase (3HSD) and P450 side-chain cleavage enzyme (P450scc)

Importantly, the proteomic similarity of Day 30 iHLOs to PHHs, with a 33.46% expression difference from liver tissue, underscores their physiological relevance compared to traditional models like HepG2 cells, which exhibit a 54.36% protein difference from liver tissue, or HepaRG cells, with a 45.40% protein difference

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If the answers are vague, youre not in a clinical planyoure in a protocol marketplace

When a request is denied, the denial letter names the criterion that was not met