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The estrogen-ER pathway is central to breast carcinogenesis, circulating oestrogens e.g

Let's clear up a few regarding glutathione, collagen, and Vitamin C

O -glycosides (e.g., isoquercitrin) are typically hydrolyzed in the upper gastrointestinal tract to release aglycones like quercetin, while C -glycosides (e.g., orientin, vitexin), due to their structural stability, are only metabolized into absorbable forms in the colon by gut microbiota (Xie et al., 2022)

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