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Weight-loss drugs, Doustdar added, increasingly resemble a consumer market one more driven by new product updates that he compared to iPhones, rather than a more traditional pharmaceutical market like for insulin, where patients find a version that works for them and usually go through insurance

DPP-4 resistance: The Aib substitution at position 8 prevents DPP-4 cleavage, which normally inactivates native GLP-1 within 2-3 minutes

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