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Electrons donated by CoQH 2 were transduced to cyt c via these three subunits sequentially

Since an IGF-1R construct, in which the tyrosine at position 1136 was replaced by a phenylalanine, also led to a strong inhibition of phosphorylated Akt in transfected cells, it was suggested that this mechanism may be responsible for the apoptotic effect of PPP (Vasilcanu et al, 2004)

Vinceti M, Urbano T, Chiari A, Filippini T, Wise LA, Tondelli M, Michalke B, Shimizu M, Saito Y

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