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Methods/design Study type This study takes the form a pragmatic, randomised, multicentre, non-inferiority clinical trial undertaken in the primary healthcare setting, with a duration of one year
There are some long-term protocols with 30 days on, 1 week-off to ensure effectiveness
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The highest activity in this model demonstrated CD34 positive elements with earliest peak at 4th day, followed by VEGF (peak at 14th day) and FVIII (peak at 21 day)
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