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In fact, sample sizes between 2500 and 6500 individuals per group would be necessary to detect a between group differences with 80% power at p 0.339) it was not further considered in any analysis

The most common side effects of GLP-1 medications like semaglutide are gastrointestinal and usually mild: nausea, occasional bloating, or constipation

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This triple-agonist approach, targeting GLP-1, GIP, and glucagon receptors, produced the most dramatic weight loss results seen in any Phase 2 obesity trial

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