note that the end of the Nco I site (CCATGG) overlaps by one base (G) with one of the priming sites
Preclinical models demonstrate that these compounds reduce reactive oxygen species, stabilize mitochondrial membrane potential, enhance mitophagy, and activate NRF2 dependent transcription, which translates into attenuation of ASD like behaviors in VPA, propionic acid, maternal immune activation, and BTBR paradigms (Yang et al., 2020
Support for connective tissue / cartilage / bone health (emerging) Some clinics suggest it may aid cartilage repair, bone density improvements, or joint health (often when paired with other peptides)
Includes vitamin B12 to complement metabolic health and nerve function
(Seoul.) 33 , 435444 (2018)