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The company has also said a substantial share of participants achieved very large weight reductions during the trial

The estimated ratio of dose- normalized geometric means of PK parameters between the highest and lowest doses was used to assess dose proportionality

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Finally, to align with 2024 CDC DPRP Standards, the CY 2025 PFS final rule (89 FR 98045) updated the MDPP definition of Online to align with the 2024 CDC DPRP definition for this delivery modality