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As illustrated in Figure 6 , Uniform Manifold Approximation and Projection (UMAP) clustering enables the clear identification of the complex renal cellular landscape, encompassing core cellular populations including endothelial cells (EC), fibroblasts (FIB), vascular smooth muscle cells/pericytes (VSM/P), immune cells (IMM), podocytes (POD), neutrophils (NEU), proximal tubule cells (PT), parietal epithelial cells (PEC), interstitial cells (IC), papillary epithelial cells (PapE), principal cells of collecting ducts (PC), connecting tubule cells (CNT), distal tubule cells (DCT), descending thin limbs (DTL), and thick ascending limbs of Henles loop (ATL and TAL) ( Figure 6A )
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3.4.2 Proinflammatory mediators PGE2 is the most abundant proinflammatory mediator in prostate tissue, with elevated levels in PC [65]
It now seems that, in Arabidopsis, DHARs are not normally required for ascorbate recycling or to maintain ascorbate redox state even under conditions that are known to stimulate glutathione oxidation without affecting ascorbate levels (Rahantaniaina et al., 2017), contrary to previously reported findings in tobacco (Chen and Gallie, 2006
