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If an abnormally high cumulative doses are administered, or the patient has low plasma pseudocholinesterase activity, then Phase I block can progress into Phase II block due to the inclusion of additional mechanisms that come into play when high synaptic levels of succinylcholine are achieved

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Sakai K, Lowman HB, Clemmons DR

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Suppressive impact of anethum graveolens consumption on biochemical risk factors of atherosclerosis in hypercholesterolemic rabbits