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While healthy lifestyle changes remain a cornerstone of our approach, semaglutide GLP-1 provides an advanced option that targets the underlying physiological drivers of obesity, offering our patients a real opportunity to reset their weight set point and achieve lasting results

In patients with type 2 diabetes, tirzepatide was shown to be noninferior and superior to semaglutide in terms of reducing HbA1c levels over a 40-week period

Lotiglipron The development of lotiglipron for obesity and T2DM was prematurely stopped in early-phase clinical trials due to its association with elevated transaminases and potential liver toxicity

The findings, published in Journal of the American Medical Association (JAMA) Psychiatry, showed that weekly injections of semaglutidecompared with placebo injectionsreduced alcohol craving, drinking quantity and the frequency of heavy drinking days in adults with symptoms of alcohol use disorder

Zhong et al., 2023)