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As of January 1, 2026, Medi-Cal no longer covers GLP-1 medications for weight loss for members 21 and older, though it still covers them for Type 2 diabetes

GLP-1 agonists like semaglutide help lower blood sugar levels by increasing the amount of insulin released by the pancreas and decreasing the amount of glucose produced by the liver, notes Chris Damman, M.D., clinical associate professor of Gastroenterology and Medicine at the University of Washington and the chief medical officer of supplement company Supergut

The risk of blood clots does not appear to be significantly higher than in the general population or compared to other medications in the same class

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