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Direct and indirect evidences of BDNF and NGF as key modulators in depression: role of antidepressants treatment
Recently, AC antioxidant activity has been verified using a cell-free system bioassay based on copper (Cu + )-induced low-density lipoproteins (LDL) peroxidation in vitro as well as the in vitro cultured cell system (HT-29 intestinal cell line) (Cardinali et al
Since metabolites are the final downstream products of transcription and translation, they are closest to the phenotype (6) and largely reflect environmental influences, nutritional requirements, effects of xenobiotics and drugs, stress, and various pathological or internal changes in biochemical pathways (7, 8)