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Some people experience no gastrointestinal issues with tirzepatide but cannot tolerate semaglutide, or vice versa

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With regard to dietary supplements , patients should be aware of the following: Herbal supplements with hypoglycaemic properties such as berberine, bitter melon, or fenugreek may enhance blood glucose-lowering effects and increase hypoglycaemia risk, particularly when used alongside insulin or sulfonylureas

The primary sources of vitamins A, C, and E are fresh vegetables and fruits, while vitamin D is primarily biosynthesized through the skin under sunlight

Management: o Dose adjustment or supplementation may be required under medical supervision