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It is an intracellular metabolic-enzyme modulator, which is why its research read-outs are things like NAD+ levels and adipocyte gene expression, not how full you feel. That mechanistic distinction is the single most important thing to understand before looking at any dose number

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Proc Natl Acad Sci USA 2001

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doi: 10.1002/rcm.2207 Summary Keywords bile, metaproteomics, gallstone, microbiome, proteomics, cholecystitis Citation Yang X-T, Wang J, Jiang Y-H, Zhang L, Du L, Li J and Liu F (2023) Insight into the mechanism of gallstone disease by proteomic and metaproteomic characterization of human bile