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Important safety considerations include a boxed warning for risk of thyroid C-cell tumors (contraindicated in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2), and risks of pancreatitis, gallbladder disease, acute kidney injury with dehydration, and diabetic retinopathy complications with semaglutide

Reconstitution & Handling Reconstitute the lyophilized Semaglutide 10mg powder with bacteriostatic water by directing the diluent gently against the vial wall never inject directly onto the pellet

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