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Over time, these factors can increase the risk of cardiovascular disease

Typical downsides are gastrointestinal: Oily spotting or discharge Urgent or more frequent bowel motions Flatulence with leakage (yes, those horror stories are mostly about orlistat) These are much more likely if you eat a highfat diet while taking it

The ones physicians and insurers most commonly accept: type 2 diabetes or prediabetes, high blood pressure, high cholesterol, obstructive sleep apnea, PCOS, fatty liver disease, and cardiovascular disease

Armstrong said parents and their children need to be aware that starting the medication will require lifestyle changes for years to come

If you're planning pregnancy, FDA guidance recommends discontinuing semaglutide approximately 2 months before a planned pregnancy and tirzepatide about 1 month before conception due to potential fetal risks