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Cellular Repair: During fasting, cells initiate repair processes, which might contribute to longevity
By supplementing with methylcobalamin, you will add the essential methyl-group to the SAM pathway that methylated folate may not be able to provide
Intriguingly, it seems that this shift in the tryptophan metabolism from serotonin to the kyn pathway is associated with BD, MDD and SZ, but only in mood disorders (BD and MDD) there was a preferential metabolism of Kyn to the potentially neurotoxic QA [231], demonstrating the biological differences in this pathway between various psychiatric disorders
Understanding this pattern helps you distinguish normal adaptation from a sign that your current dose or formulation needs adjustment
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