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They help regulate blood sugar, reduce appetite, and support testing blood glucose levels

Six studies used a composite outcome, and the component outcomes differed

In the large cardiovascular outcomes trial reported in the Wegovy label, systolic blood pressure fell by a mean of 3.8 mmHg with semaglutide versus 0.5 mmHg with placebo at week 104, a difference of 3.3 mmHg from a baseline of 131 mmHg

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[1] [2] This reduces the risk of hypoglycaemia when used alone, though this risk increases significantly when combined with insulin or sulfonylureas